| ncRNA name | FN siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | retinas |
| Methods | siRNA injection, Western blot, electron microscopy, retinal trypsin digest |
| Expression pattern | associated |
| Functional description | FN-siRNA treatment reduced FN overexpression and BM thickening (145±19.9% of control and 56.4±2.8 nm, respectively) and significantly reduced the number of acellular capillaries (35%) and pericyte loss (55%) compared to those of untreated diabetic eyes. |
| PubMed ID | 22171163 |
| Year | 2011 |
| Title | A long-term siRNA strategy regulates fibronectin overexpression and improves vascular lesions in retinas of diabetic rats. |
| Drug-related ncRNA | NO |
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